NHA Certified Clinical Medical Assistant (CCMA) guideStudy & preparation
CCMA Infection Control: Standard Precautions, OSHA Sharps Rules, and Sterilization
Infection Control and Safety carries 15 of the CCMA's 150 scored questions. Here is what NHA's test plan lists, with the CDC and OSHA rules behind each topic: the chain of infection, precautions, hand hygiene, PPE order, sterilization, sharps, exposures and safety data sheets.
Short answer
Infection Control and Safety (subdomain 3C) carries 15 of the CCMA's 150 scored questions, as many as Foundational Knowledge and Basic Science. Its nine tasks and 19 knowledge statements cover the chain of infection, universal, standard and transmission-based precautions, hand hygiene, PPE donning and doffing, cleaning, disinfection and sterilization, OSHA's sharps and biohazard rules, post-exposure steps and safety data sheets. The rules come from CDC and OSHA: for example, OSHA bars recapping contaminated needles unless no alternative is feasible, and then only one-handed or with a device.
Infection control on the CCMA is a subject of exact rules, and NHA's CCMA test plan gives Infection Control and Safety 15 scored questions and names the authorities itself: "CDC guidelines for infectious disease" (k96), "guidelines for exposure to bloodborne pathogens (for example, OSHA...)" (k97), and disposal "as dictated by Occupational Safety and Health Administration (OSHA)" (task 3C8). This guide follows those sources, as checked on October 28, 2026.
What subdomain 3C covers
The nine tasks: follow standard and universal precautions (3C1) and infectious disease guidelines (3C2), use PPE including donning and doffing (3C3), hand hygiene (3C4), disinfection and sanitization (3C5), sterilization of equipment (3C6), aseptic technique (3C7), OSHA biohazard disposal such as sharps containers and biohazard bags (3C8), and post-exposure steps such as needle safety and eyewash stations (3C9).
The 19 knowledge statements (k92–k110) add pathogens and nonpathogens, the chain of infection, signs of infectious disease, epidemics and pandemics, alcohol-based rubs, sterilization techniques, medical and surgical asepsis, the order of cleaning and cleaning products, safety data sheets, chemical cautions, disposal methods, the exposure control plan, and logs for maintenance, temperature and quality control.
The chain of infection
CDC's epidemiology course describes the chain this way: transmission occurs when the agent leaves its reservoir or host through a portal of exit, is conveyed by a mode of transmission, and enters through a portal of entry to infect a susceptible host. Each link is a place to break the chain. Passy's mapping of this subdomain's topics onto the links:
| Link | Example of breaking it |
|---|---|
| Infectious agent and reservoir | Cleaning, disinfection and sterilization |
| Portal of exit | Respiratory hygiene, covering wounds |
| Mode of transmission | Hand hygiene, PPE, transmission-based precautions |
| Portal of entry | Aseptic technique, sharps safety |
| Susceptible host | Immunization, such as hepatitis B vaccination for exposed workers |
CDC divides transmission into direct (direct contact and droplet spread) and indirect (airborne particles, vehicles such as objects, and vectors).
Universal, standard and transmission-based precautions
The test plan lists universal precautions (k99) and standard precautions (k100) separately, and they aren't the same thing:
- Universal precautions is OSHA's term. In the bloodborne pathogens standard, it means "all human blood and certain human body fluids are treated as if known to be infectious for HIV, HBV, and other bloodborne pathogens"
- Standard precautions is CDC's broader set for all patient care. CDC's standard precautions page lists hand hygiene, PPE "whenever there is an expectation of possible exposure to an infectious material," respiratory hygiene and cough etiquette, patient placement, cleaning and disinfecting equipment, devices and the environment, careful handling of textiles and laundry, and safe injection practices
- Transmission-based precautions are used "in addition to Standard Precautions," per CDC's transmission-based precautions page
| Precaution | Patient placement | PPE and source control |
|---|---|---|
| Contact | Single room if available in acute care hospitals; in ambulatory settings, an exam room or cubicle as soon as possible | Gown and gloves for all interactions with the patient or the patient's environment; disposable or dedicated equipment such as blood pressure cuffs, or clean and disinfect it before the next patient |
| Droplet | Single room if possible; in ambulatory settings, an exam room or cubicle as soon as possible | A mask on the patient; staff put on a mask on entering the room or patient space |
| Airborne | Airborne infection isolation room (AIIR); where none exists, a masked patient in a private room with the door closed until transfer or discharge home | A mask on the patient; a fit-tested NIOSH-approved N95 or higher-level respirator for staff |
CDC's airborne examples are tuberculosis, measles, chickenpox and disseminated herpes zoster. If a question is set in a medical office or clinic, the ambulatory placements in the table are the ones that apply.
Hand hygiene rules from CDC and OSHA
CDC's hand hygiene page for health care workers sets these rules:
- Alcohol-based hand sanitizer is the default. Unless hands are visibly soiled, CDC prefers it over soap and water in most clinical situations, and recommends at least 60% alcohol
- Soap and water when hands are visibly soiled, before eating, after using the restroom, and as an added precaution after caring for patients with C. difficile or norovirus during outbreaks
- Timing. About 20 seconds to rub sanitizer in; at least 15 seconds of vigorous washing, and CDC notes others recommend 20
- Gloves don't replace it. "Gloves are not a substitute for hand hygiene"
OSHA adds the legal duty: employers must ensure workers "wash their hands immediately or as soon as feasible after removal of gloves or other personal protective equipment," and where no sink is available and antiseptic cleanser is used, hands must be washed with soap and running water as soon as feasible.
PPE: the order for putting it on and taking it off
CDC's PPE sequence poster (CS250672-E) gives the order. It notes that the type of PPE varies with the precautions required.
| Putting on | Removing, CDC example 1 | Removing, CDC example 2 |
|---|---|---|
| 1. Gown | 1. Gloves | 1. Gown and gloves together |
| 2. Mask or respirator | 2. Goggles or face shield | 2. Goggles or face shield |
| 3. Goggles or face shield | 3. Gown | 3. Mask or respirator |
| 4. Gloves, extended to cover the gown's wrist | 4. Mask or respirator | 4. Hand hygiene |
| 5. Hand hygiene |
The poster adds three details worth knowing: remove all PPE before leaving the patient room except a respirator, which comes off after you leave and close the door; grasp a mask's bottom ties or elastics, then the top, without touching the front; and perform hand hygiene between steps if your hands become contaminated. OSHA's standard requires the employer to provide PPE at no cost, gloves whenever hand contact with blood or other potentially infectious materials can be anticipated, and masks with eye protection or face shields whenever splashes or sprays are possible.
Sequences are recall items, so a deck you review daily helps, and 580 planned CCMA flashcards are sorted by domain for that kind of review.
Cleaning, disinfection and sterilization
CDC's rational approach to disinfection and sterilization sorts patient-care items by risk:
| Category | What it touches | Processing | CDC examples |
|---|---|---|---|
| Critical | Sterile tissue or the vascular system | Sterilization | Surgical instruments, implants, urinary and cardiac catheters |
| Semicritical | Mucous membranes or nonintact skin | At least high-level disinfection | Respiratory therapy and anesthesia equipment, some endoscopes, laryngoscope blades |
| Noncritical | Intact skin only | Low-level disinfection | Blood pressure cuffs, bedpans, crutches |
CDC defines high-level disinfection as eliminating all microorganisms "except for small numbers of bacterial spores." Sterilization goes further, which is why critical items need it.
For sterilization in the office autoclave, CDC's steam sterilization page gives the two common temperatures and minimum times for wrapped supplies: 121 °C (250 °F) for 30 minutes in a gravity displacement sterilizer, or 132 °C (270 °F) for 4 minutes in a prevacuum sterilizer. CDC's recommendations add:
- Clean first. "Meticulously clean patient-care items with water and detergent" before high-level disinfection or sterilization
- Monitor every load with mechanical and chemical indicators, internal and external
- Biological indicators at least weekly, using spores of Geobacillus stearothermophilus for steam
- Storage. Under event-related storage, sterile packs stay usable "unless the packaging is compromised"; under time-related storage, label each pack with an expiration date
The order of cleaning
Knowledge statement k105 asks for the "order of cleaning." CDC's environmental cleaning procedures, written for health care facilities with limited resources, give two rules that work in any setting: proceed from cleaner to dirtier areas, and proceed from high to low, so dirt doesn't fall onto areas already cleaned. CDC's examples: bed rails before bed legs, surfaces before floors, floors last. For a blood spill, the same page says to wipe it up with absorbent material, clean with detergent and water, then disinfect with a facility-approved intermediate-level disinfectant. The U.S. legal duty is OSHA's: contaminated work surfaces must be decontaminated with an appropriate disinfectant "immediately or as soon as feasible" after any spill of blood or other potentially infectious materials. The WHO phlebotomy guideline gives one example concentration, a 1:10 dilution of 5.25% bleach left wet for 10 minutes on surfaces that tolerate it, prepared fresh daily.
OSHA's bloodborne pathogens rules for medical assistants
The bloodborne pathogens standard is the federal rule behind tasks 3C8 and 3C9. The points most likely to appear as questions:
| Topic | What 29 CFR 1910.1030 requires |
|---|---|
| Recapping and bending | Contaminated needles and sharps "shall not be bent, recapped, or removed" unless no alternative is feasible, and then only with a mechanical device or a one-handed technique; shearing or breaking is prohibited |
| Sharps containers | Closable, puncture resistant, leakproof on the sides and bottom, labeled or color-coded; close to where sharps are used, kept upright, replaced routinely and not allowed to overfill |
| Labels | Biohazard labels that are "fluorescent orange or orange-red or predominantly so"; red bags or red containers may substitute |
| Specimens | Containers that prevent leakage; labels can be skipped inside a facility that handles all specimens with universal precautions, but are required when specimens leave it |
| Food and drink | No eating, drinking, smoking, cosmetics or contact lens handling where exposure is likely; no food in refrigerators holding blood |
| Hepatitis B vaccine | Offered at no cost, after training and within 10 working days of initial assignment; an employee who declines signs the standard's declination statement and can still get the vaccine later |
| Exposure control plan | Reviewed and updated at least annually |
| Training | At initial assignment and at least annually |
| Sharps injury log | Required for employers who must keep OSHA injury and illness logs |
After an exposure
The standard defines an exposure incident as eye, mouth, other mucous membrane, nonintact skin or parenteral contact with blood or other potentially infectious materials. Its steps:
- Wash or flush immediately. Wash skin with soap and water, or flush mucous membranes with water, "immediately or as soon as feasible"
- Report it, so the employer can make immediately available a confidential medical evaluation and follow-up
- Follow-up includes documenting the route and circumstances, testing the source individual's blood when consent is obtained, testing the exposed worker's blood, post-exposure prophylaxis "when medically indicated, as recommended by the U.S. Public Health Service," and counseling
The WHO phlebotomy guideline adds the urgency: don't delay post-exposure prophylaxis, because beyond 72 hours it is not effective. For chemical splashes, OSHA's first-aid rule, 29 CFR 1910.151(c), requires facilities for quick drenching or flushing of the eyes and body within the work area wherever people may be exposed to injurious corrosive materials. Blood or other potentially infectious material in the eyes falls under step 1 above: flush with water immediately or as soon as feasible.
Safety data sheets
Under OSHA's hazard communication standard, employers must keep a safety data sheet for each hazardous chemical they use, "readily accessible during each work shift," on paper or electronically as long as access has no barriers. Every SDS is in English and has 16 numbered sections in a fixed order, starting with Section 1, Identification, and Section 2, Hazard(s) identification, with first-aid measures in Section 4, handling and storage in Section 7 and exposure controls and personal protection in Section 8.
Three infection control practice questions written by Passy
These are original questions in the exam's style. They aren't NHA items.
1. A medical assistant wore a gown, a mask, goggles and gloves. Following CDC's first example sequence, which item comes off first?
- A. Gloves
- B. Mask
- C. Goggles
- D. Gown
Keyed answer: A. CDC's first example removes gloves, then goggles or face shield, then the gown, then the mask or respirator, followed by hand hygiene. The mask is last in both of CDC's examples, and the gown comes off first only when it is removed together with the gloves.
2. Under CDC's classification of patient-care items, how should a reusable blood pressure cuff be processed between patients?
- A. Sterilization, as a critical item
- B. High-level disinfection, as a semicritical item
- C. Low-level disinfection, as a noncritical item
- D. Disposal after a single patient use
Keyed answer: C. A blood pressure cuff touches only intact skin, and CDC lists it among its noncritical examples. Critical items enter sterile tissue, semicritical items touch mucous membranes, and option D isn't a CDC requirement for a reusable cuff.
3. What does OSHA's bloodborne pathogens standard say about recapping a contaminated needle?
- A. Only if no alternative exists, one-handed or by device
- B. Allowed with two hands if gloves are worn
- C. Required before the needle goes in a sharps container
- D. Allowed if the cap rests on a clean surface first
Keyed answer: A. 29 CFR 1910.1030(d)(2)(vii) bars recapping unless the employer can show no alternative is feasible or a procedure requires it, and then only with a mechanical device or a one-handed technique. Options B, C and D all describe two-handed or routine recapping, which the rule doesn't allow.
Wrong answers on sequences tend to repeat, so it helps when they come back, and Redemption challenges in planned CCMA prep bring back the questions you missed.
How to study infection control for the CCMA
The CCMA study plan guide gives this subdomain about 6 of 60 hours. A way to use them, in Passy's words:
- Hour 1: the chain of infection and the three kinds of precautions, with one example disease for each transmission-based type
- Hour 2: hand hygiene and PPE order until you can write both from memory
- Hours 3 and 4: the CDC item categories, steam sterilization numbers and the order of cleaning
- Hours 5 and 6: the OSHA table, the exposure steps and the SDS sections, then mixed practice
These rules also run through the other clinical subdomains: sharps and exposure steps apply to every draw in the CCMA order of draw guide, and to every injection in the Clinical Patient Care guide. When you've finished the six hours, every missed infection control question waits in planned Fix It review for a second try.
Your next step with infection control
Write the PPE donning and removal orders and the CDC item categories from memory, then check them against the tables above. Then try the 20 free CCMA practice questions, which include a sharps safety scenario.
Trust the source
Official sources
Exam policies can change. Use these primary sources for the most current details.
- NHA Certified Clinical Medical Assistant (CCMA) Test PlanNational Healthcareer Association↗
- Principles of Epidemiology, Lesson 1, Section 10: Chain of InfectionCenters for Disease Control and Prevention↗
- Standard Precautions for All Patient CareCenters for Disease Control and Prevention↗
- Transmission-Based PrecautionsCenters for Disease Control and Prevention↗
- Clinical Safety: Hand Hygiene for Healthcare WorkersCenters for Disease Control and Prevention↗
- Sequence for Putting On Personal Protective Equipment (PPE) (CS250672-E)Centers for Disease Control and Prevention↗
- A Rational Approach to Disinfection and SterilizationCenters for Disease Control and Prevention↗
- Steam SterilizationCenters for Disease Control and Prevention↗
- Recommendations for Disinfection and Sterilization in Healthcare FacilitiesCenters for Disease Control and Prevention↗
- Environmental Cleaning ProceduresCenters for Disease Control and Prevention↗
- 29 CFR 1910.1030, Bloodborne pathogensElectronic Code of Federal Regulations (OSHA)↗
- 29 CFR 1910.1200, Hazard communicationElectronic Code of Federal Regulations (OSHA)↗
- 29 CFR 1910.151, Medical services and first aidElectronic Code of Federal Regulations (OSHA)↗
- WHO guidelines on drawing blood: best practices in phlebotomyWorld Health Organization↗